1. The Democratic Party is going to have to make a very, very profound and important decision.

2. This could have a profound effect on your IT department this holiday season.

3. A sudden loss like this can have a profound effect on the entire school community.

4. If these countries break down, that has profound effects on all of us.

5. Sometimes the most profound solution is to change the entire problem.

6. They have had a very profound effect on me.

7. The inability of our best robots to make a profound effect in the short term was disastrous.

8. Her death would have unfolded as a private tragedy had her parents not made a profound choice.

9. The Danish people really have a profound respect for the president.

10. There are profound consequences from the scale and ambition of this trend.

11. The level of distrust between them has never been more profound, Kerry said.

12. We must not allow the profound pain, fatigue and stress that we have now to turn into resignation.

13. This was a sensible and profound point, and something Yahoo never accomplished.

14. She had heard that Betty Ford is a really profound rehab.

15. Nothing visually profound is being produced here, I would have to say.